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Invitrogen
ERP44 Polyclonal Antibody
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ERP44 Antibody (PA5-109693) in WB
Western blot analysis of ERP44 in extracts of various cell lines. Samples were incubated with ERP44 Polyclonal antibody (Product # PA5-109693) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-109693
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 57-406 of human ERP44 (NP_055866.1).
偶联物
形式
Liquid
浓度
1.71 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: WCRFSQMLHP IFEEASDVIK EEFPNENQVV FARVDCDQHS DIAQRYRISK YPTLKLFRNG MMMKREYRGQ RSVKALADYI RQQKSDPIQE IRDLAEITTL DRSKRNIIGY FEQKDSDNYR VFERVANILH DDCAFLSAFG DVSKPERYSG DNIIYKPPGH SAPDMVYLGA MTNFDVTYNW IQDKCVPLVR EITFENGEEL TEEGLPFLIL FHMKEDTESL EIFQNEVARQ LISEKGTINF LHADCDKFRH PLLHIQKTPA DCPVIAIDSF RHMYVFGDFK DVLIPGKLKQ FVFDLHSGKL HREFHHGPDP TDTAPGEQAQ DVASSPPESS FQKLAPSEYR YTLLRDRDEL
靶标信息
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endoplasmic reticulum resident protein 44; endoplasmic reticulum resident protein 44 kDa; endoplasmic reticulum resident protein 44kDa; endoplasmic reticulum resident protein ERp44; ER protein 44; OTTHUMP00000063799; protein disulfide isomerase family A, member 10; thioredoxin domain containing 4 (endoplasmic reticulum); Thioredoxin domain-containing protein 4
基因别名: 1110001E24Rik; AI849526; AL033348; BWK4; ERP44; KIAA0573; PDIA10; TXNDC4; UNQ532/PRO1075
UniProt ID: (Human) Q9BS26, (Mouse) Q9D1Q6
Entrez Gene ID: (Human) 23071, (Mouse) 76299, (Rat) 298066
