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Invitrogen
ETFDH Polyclonal Antibody
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ETFDH Antibody (PA5-109695) in WB
Western blot analysis of ETFDH in extracts of various cell lines. Samples were incubated with ETFDH Polyclonal antibody (Product # PA5-109695) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
产品信息
PA5-109695
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 318-617 of human ETFDH (NP_004444.2).
偶联物
形式
Liquid
浓度
0.92 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LVALGLVVGL DYQNPYLSPF REFQRWKHHP SIRPTLEGGK RIAYGARALN EGGFQSIPKL TFPGGLLIGC SPGFMNVPKI KGTHTAMKSG ILAAESIFNQ LTSENLQSKT IGLHVTEYED NLKNSWVWKE LYSVRNIRPS CHGVLGVYGG MIYTGIFYWI LRGMEPWTLK HKGSDFERLK PAKDCTPIEY PKPDGQISFD LLSSVALSGT NHEHDQPAHL TLRDDSIPVN RNLSIYDGPE QRFCPAGVYE FVPVEQGDGF RLQINAQNCV HCKTCDIKDP SQNINWVVPE GGGGPAYNGM
靶标信息
Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; electron transferring flavoprotein dehydrogenase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; ETF-QO; ETF-ubiquinone oxidoreductase
基因别名: 0610010I20Rik; AV001013; ETFDH; ETFQO; MADD
UniProt ID: (Human) Q16134, (Mouse) Q921G7
Entrez Gene ID: (Human) 2110, (Rat) 295143, (Mouse) 66841
electron-transferring-flavoprotein dehydrogenase activity
electron carrier activity
oxidoreductase activity
oxidoreductase activity, oxidizing metal ions with flavin as acceptor
metal ion binding
quinone binding
ubiquinone binding
flavin adenine dinucleotide binding
4 iron, 4 sulfur cluster binding
iron-sulfur cluster binding
oxidoreductase
