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Invitrogen
EWSR1 Polyclonal Antibody
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产品信息
PA1-27592
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to human RNA-binding protein EWSR1, amino acids 380-488
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-27592 detects EWSR1 from human, mouse, and rat samples.
PA1-27592 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
Synthetic peptide corresponding to human RNA-binding protein EWSR1, amino acids 380-488
靶标信息
This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a ttranslocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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