Proteintech

EYA1 Polyclonal Antibody

查看其他6个EYA1抗体

问题与答案

问题与答案

问题与答案

抗体检测数据 (1)

EYA1 Antibody in Western Blot (WB)

EYA1 Antibody in Western Blot (WB)

图: 1 / 1

EYA1 Antibody (31435-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with 31435-1-AP (EYA1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

EYA1 Antibody in Western Blot (WB)

Product Image Gallery

EYA1 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with 31435-1-AP (EYA1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

Immunogen image

EYA1 Polyclonal Antibody

Immunogen Image EYA1 Polyclonal Antibody

产品信息

31435-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

-

酶联免疫吸附实验 (ELISA)

Assay-dependent

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

EYA1 fusion protein Ag33438

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.35 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

产品详细信息

Immunogen sequence: TPSSQTMAAY GQTQFTTGMQ QATAYATYPQ PGQPYGISSY GALWAGIKTE GGLSQSQSPG QTGFLSYGTS FSTPQPGQAP YSYQMQGSSF TTSSGIYTGN NSLTNSSGFN SSQQDYPSYP SFGQGQYAQY YNSSPYPAHY MTSSNTSPTT P

靶标信息

This gene encodes a member of the eyes absent family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: EYA transcriptional coactivator and phosphatase 1; Eyes absent; eyes absent 1 homolog; Eyes absent homolog 1; MGC141875; OTTHUMP00000195053

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基因别名: BOP; BOR; BOS1; EYA1; OFC1

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UniProt ID: (Human) Q99502, (Mouse) P97767

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Entrez Gene ID: (Human) 2138, (Mouse) 14048, (Rat) 502935

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RNA binding protein tyrosine phosphatase activity protein binding metal ion binding phosphoprotein phosphatase activity hydrolase activity molecular_function

establishment of mitotic spindle orientation metanephros development branching involved in ureteric bud morphogenesis outflow tract morphogenesis double-strand break repair transcription, DNA-templated pattern specification process mesodermal cell fate specification sensory perception of sound anatomical structure morphogenesis response to ionizing radiation striated muscle tissue development histone dephosphorylation protein sumoylation cellular protein localization establishment or maintenance of apical/basal cell polarity peptidyl-tyrosine dephosphorylation aorta morphogenesis outer ear morphogenesis middle ear morphogenesis regulation of neuron differentiation positive regulation of DNA repair positive regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter neuron fate specification embryonic skeletal system morphogenesis semicircular canal morphogenesis positive regulation of epithelial cell proliferation pharyngeal system development lung epithelial cell differentiation otic vesicle morphogenesis positive regulation of secondary heart field cardioblast proliferation cochlea morphogenesis negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ureteric bud development DNA repair regulation of transcription, DNA-templated protein dephosphorylation cellular response to DNA damage stimulus multicellular organism development organ morphogenesis chromatin modification ear morphogenesis inner ear morphogenesis cell fate commitment positive regulation of transcription, DNA-templated anatomical structure development otic vesicle development biological_process