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Alomone Labs, LTD
EphA1 (extracellular) Polyclonal Antibody
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图: 1 / 5
EphA1 (extracellular) Antibody (AER-011-200UL) in ICC/IF
Expression of EphA1 in human MCF-7 cells - Cell surface detection of EphA1 in live intact MCF-7 breast adenocarcinoma cells. Cells were stained with Anti-EphA1 (extracellular) Antibody (#AER-011), (1:25) followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody (red). B. Live image of the cells stained in A. C. Merge image of A and B.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
AER-011-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KKEPRQLELTWAGSR, corresponding to amino acid residues 457-471 of human EphA1, Extracellular, N-terminus
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
规格
160 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: embryonic stem cell kinase; eph tyrosine kinase 1; ephrin receptor EphA1; erythropoietin-producing hepatoma amplified sequence; erythropoietin-producing hepatoma receptor; hEpha1; mEpha1; MGC163163; oncogene EPH; tyrosine kinase receptor precursor (put.); putative; tyrosine-protein kinase receptor EPH; tyrosine-protein kinase receptor ESK; unnamed protein product
基因别名: 5730453L17Rik; EPH; EPHT; EPHT1; Esk
UniProt ID: (Human) P21709, (Mouse) Q60750
Entrez Gene ID: (Human) 2041, (Rat) 312279, (Mouse) 13835
positive regulation of cell-matrix adhesion
transmembrane receptor protein tyrosine kinase signaling pathway
regulation of cell adhesion
positive regulation of cell migration
negative regulation of cell migration
substrate adhesion-dependent cell spreading
positive regulation of angiogenesis
ephrin receptor signaling pathway
positive regulation of stress fiber assembly
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