Invitrogen

EpoR Monoclonal Antibody (C2)

Name: EpoR Monoclonal Antibody (C2)
Brand: Invitrogen
SKU: MA566069

查看其他29个EpoR抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

EpoR Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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EpoR Antibody (MA566069) in IHC (P)

Immunohistochemistry analysis of EpoR in paraffin-embedded Mouse Cardiac Muscle tissue. Samples were incubated with EpoR Monoclonal (Product # MA566069) antibody using a dilution of 20 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG (2 µg/mL) and DAB.

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Immunogen image

Immunogen Image EpoR Monoclonal Antibody (C2)

产品信息

MA566069

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

5-20 µg/mL

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

抗原

Recombinant Erythropoietin Receptor (EPOR) (Pro33-Leu210)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

EpoR encodes the erythropoietin receptor, which belongs to the cytokine receptor family. When erythropoietin binds to this receptor, it activates the Jak2 tyrosine kinase, which in turn activates various intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. The stimulated erythropoietin receptor plays a role in the survival of erythroid cells. Defects in this gene may result in erythroleukemia and familial erythrocytosis. Dysregulation of this gene may also affect the growth of certain tumors. Multiple transcript variants are produced as a result of alternate splicing. Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。