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Invitrogen
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Immunogen sequence: PKNSDPWAAS QQPASSAGKR ASDAWGAVST TKPVSVSGSF ELFSNLNGTI KDDFSEFDNL RTSKKTAESV TSLPSQN
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.
Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.
仅用于科研。不用于诊断过程。未经明确授权不得转售。