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Invitrogen
FABP5 Polyclonal Antibody
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FABP5 Antibody (PA5-47143) in IHC (P)
Immunohistochemical analysis of FABP5 in immersion fixed paraffin-embedded sections of mouse skin (ear) tissue. Samples were incubated with FABP5 polyclonal antibody (Product # PA5-47143) using a dilution of 3 µg/mL for 1 hour at room temperature followed by Anti-Goat IgG VisUCyte™ HRP Polymer Antibody. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-47143
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant mouse FABP5/E-FABP Met1-Gln135
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In Western blots, less than 5% cross-reactivity with recombinant mouse FABP4 and recombinant human (rh) FABP3 is observed and less than 1% cross-reactivity with recombinant rat (rr) FABP2 and rrFABP1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
FABP5 (fatty acid binding protein 5 (psoriasis-associated)) is a proteinthat in humans is encoded by theFABP5 gene, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog. It is a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. The PAFABP cDNA encodes a 135-amino acid protein with molecular weight 15,164. This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated inpsoriasistissue. It is though that FABPs roles include fatty acid uptake, transport, and metabolism. Kaczocha et al. (2009) identifiedFABP5and FABP7 as cytosolic proteins that transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where it is hydrolyzed and inactivated. FABP3 did not show this specific transport function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 15.2 kDa fatty acid binding protein/FABP/C-FAPB homolog; cutaneous fatty acid-binding protein; E-FABPPAFABP; epidermal-type fatty acid-binding protein; epithelial fatty acid-binding protein; fatty acid binding protein 5 (psoriasis-associated); fatty acid binding protein 5, epidermal; fatty acid-binding protein, epidermal; keratinocyte lipid-binding protein; PA-FABPepidermal; psoriasis-associated fatty acid-binding protein homolog; unnamed protein product
基因别名: C-FABP; DA11; E-FABP; EFABP; Fabpe; KFABP; Klbp; mal1; PA-FABP; PAFABP
UniProt ID: (Human) Q01469, (Mouse) Q05816, (Rat) P55053
Entrez Gene ID: (Human) 2171, (Mouse) 16592, (Rat) 140868
glucose metabolic process
lipid metabolic process
phosphatidylcholine biosynthetic process
negative regulation of glucose transport
fatty acid transport
long-chain fatty acid transport
regulation of prostaglandin biosynthetic process
positive regulation of peroxisome proliferator activated receptor signaling pathway
glucose homeostasis
regulation of sensory perception of pain
retrograde trans-synaptic signaling by endocannabinoid
regulation of retrograde trans-synaptic signaling by endocanabinoid
positive regulation of cold-induced thermogenesis
lipid transport across blood brain barrier
epidermis development
triglyceride catabolic process
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