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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • FADS1 Antibodies

          Invitrogen

          FADS1 Recombinant Rabbit Monoclonal Antibody (JE55-63)

          1 篇参考文献
          查看其他14个FADS1抗体

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          Cite FADS1 Recombinant Rabbit Monoclonal Antibody (JE55-63)

          • 抗体检测数据 (10)
          FADS1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          FADS1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          图: 1 / 10

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          FADS1 Antibody (MA5-42500) in ICC/IF

          Immunocytochemistry-Immunofluorescence analysis of of FADS1 in PANC-1 cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with FADS1 Recombinant Monoclonal Antibody (Product # MA5-42500) at a dilution of 1:50 for 1 hour at room temperature, washed with PBS. Alexa Fluor 488 Goat anti-Rabbit IgG was used as the secondary antibody at 1:1,000 dilution. The nuclear counter stain is DAPI (blue)... View More {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
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          查看产品

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          FADS1 Antibody in Immunocytochemistry (ICC/IF)
          FADS1 Antibody in Immunocytochemistry (ICC/IF)
          FADS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FADS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FADS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FADS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FADS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FADS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FADS1 Antibody in Western Blot (WB)
          FADS1 Antibody in Flow Cytometry (Flow)
          FADS1 Recombinant Rabbit Monoclonal Antibody (JE55-63)

          产品信息

          MA5-42500

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:500-1:1,000
          -

          免疫组化(石蜡) (IHC (P))

          1:50-1:200
          查看1篇已发表文章 1篇已发表文章

          免疫细胞化学 (ICC/IF)

          1:50-1:100
          -

          流式细胞分析 (Flow)

          1:50-1:100
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          已发表种属

          C. elegans

          宿主/亚型

          Rabbit / IgG

          Expression System

          HEK293 cells

          分类

          Recombinant Monoclonal

          类型

          Antibody

          克隆号

          JE55-63

          抗原

          Synthetic peptide within N-terminal Human FADS1
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Protein A

          保存液

          TBS, pH 7.4, with 40% glycerol, 0.05% BSA

          内含物

          0.05% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2911641

          产品详细信息

          Positive Control: Rat liver tissue lysate, mouse liver tissue lysate, mouse brain tissue lysate, rat lung tissue lysate, Hela cell lysate, A549 cell lysate, Hela, PANC-1, human liver carcinoma tissue, human thyroid tissue, human colon carcinoma tissue, human breast carcinoma tissue, human stomach carcinoma tissue, human small intestine tissue, A549.

          Subcellular Location: Mitochondrion, Endoplasmic reticulum membrane.

          靶标信息

          The protein encoded by this gene is a member of the fatty acid desaturase gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13. 1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          生物信息学

          蛋白别名: Acyl-CoA (8-3)-desaturase; BC269730_2; D5D; delta(5) desaturase; Delta(5) fatty acid desaturase; delta-5 desaturase; delta-5 fatty acid desaturase; Fatty acid desaturase 1; FLJ38956; FLJ90273; linoleoyl-CoA desaturase (delta-6-desaturase)-like 1

          查看更多 收起

          基因别名: 0710001O03Rik; A930006B21Rik; AI317215; D5D; DSD; FADS1; FADS6; FADSD5; LLCDL1; TU12

          查看更多 收起

          UniProt ID: (Human) O60427, (Mouse) Q920L1, (Rat) Q920R3

          查看更多 收起

          Entrez Gene ID: (Human) 3992, (Mouse) 76267, (Rat) 84575

          查看更多 收起

          功能
          C-5 sterol desaturase activity oxidoreductase activity omega-6 fatty acid desaturase activity linoleoyl-CoA desaturase activity acyl-CoA desaturase activity oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water iron ion binding heme binding
          参与通路
          regulation of transcription, DNA-templated unsaturated fatty acid biosynthetic process cell-cell signaling phospholipid biosynthetic process cellular response to starvation alpha-linolenic acid metabolic process linoleic acid metabolic process regulation of cell differentiation icosanoid biosynthetic process oxidation-reduction process lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process transport arachidonic acid metabolic process long-chain fatty acid biosynthetic process aging response to nutrient response to sucrose response to organic substance response to organic cyclic compound response to insulin response to vitamin A response to isolation stress
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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