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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: REGHCYKLVSI ISKTVVLGLA LRREGPAPLH FLLLTDTPRF ALPQGLLAGD PRVERLVRDS ASYCRERFDP DEY
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
FAM59B is related to the FAM59A protein (also known as GAREM). While little is known of the role of the FAM59B protein, FAM59A is a downstream molecule in the EGF signaling pathway and binds Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. Like FAM59A, FAM59B may play a role in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GRB2-associated and regulator of MAPK protein 2; GRB2-associated and regulator of MAPK1-like
基因别名: FAM59B; GAREM2; GAREML; HRIHFB2063; KIAA2038
Entrez Gene ID: (Human) 150946