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Abnova
FAM65A Polyclonal Antibody, MaxPab™
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产品信息
H00079567-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FAM65A (AAI56640.1, 1 a.a. approximately 1219 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MMSLSVRPQR RLLSARVNRS QSFAGVLGSH ERGPRSFPVF SPPGPPRKPP ALSRVSRMFS VAHPAAKVPQ PERLDLVYTA LKRGLTAYLE VHQQEQEKLQ GQIRESKRNS RLGFLYDLDK QVKSIERFLR RLEFHASKID ELYEAYCVQR RLRDGAYNMV RAYTTGSPGS REARDSLAEA TRGHREYTES MCLLESELEA QLGEFHLRMK GLAGFARLCV GDQYEICMKY GRQRWKLRGR IEGSGKQVWD SEETIFLPLL TEFLSIKVTE LKGLANHVVV GSVSCETKDL FAALPQVVAV DINDLGTIKL SLEVTWSPFD KDDQPSAASS VNKASTVTKR FSTYSQSPPD TPSLREQAFY NMLRRQEELE NGTAWSLSSE SSDDSSSPQL SGTARHSPAP RPLVQQPEPL PIQVAFRRPE TPSSGPLDEE GAVAPVLANG HAPYSRTLSH ISEASVDAAL AEASVEAVGP ESLAWGPSPP THPAPTHGEH PSPVPPALDP GHSATSSTLG TTGSVPTSTD PAPSAHLDSV HKSTDSGPSE LPGPTHTTTG STYSAITTTH SAPSPLTHTT TGSTHKPIIS TLTTTGPTLN IIGPVQTTTS PTHTMPSPTH TTASPTHTST SPTHTPTSPT HKTSMSPPTT TSPTPSGMGL VQTATSPTHP TTSPTHPTTS PILINVSPST SLELATLSSP SKHSDPTLPG TDSLPCSPPV SNSYTQADPM APRTPHPSPA HSSRKPLTSP APDPSESTVQ SLSPTPSPPT PAPQHSDLCL AMAVQTPVPT AAGGSGDRSL EEALGALMAA LDDYRGQFPE LQGLEQEVTR LESLLMQRQG LTRSRASSLS ITVEHALESF SFLNEDEDED NDVPGDRPPS SPEAGAEDSI DSPSARPLST GCPALDAALV RHLYHCSRLL LKLGTFGPLR CQEAWALERL LREARVLEAV CEFSRRWEIP ASSAQEVVQF SASRPGFLTF WDQCTERLSC FLCPVERVLL TFCNQYGARL SLRQPGLAEA VCVKFLEDAL GQKLPRRPQP GPGEQLTVFQ FWSFVETLDS PTMEAYVTET AEEVLLVRNL NSDDQAVVLK ALRLAPEGRL RRDGLRALSS LLVHGNNKVM AAVSTQLRSL SLGPTFRERA LLCFLDQLED EDVQTRVAGC LALGCIKAPE GIEPLVYLCQ TDTEAVREAA RQSLQQCGEE GQSAHRRLEE SLDALPRIFG PGSMASTAF
靶标信息
Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: family with sequence similarity 65, member A; FLJ13725; Rho family-interacting cell polarization regulator 1
基因别名: FAM65A; KIAA1930; RIPOR1
UniProt ID: (Human) Q6ZS17
Entrez Gene ID: (Human) 79567
