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Invitrogen
FAT3 Polyclonal Antibody
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产品信息
PA5-55449
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human FAT3
偶联物
形式
Liquid
浓度
0.05 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: CLDSVILNNN ELPLQNKRSS FAEVVGLTEL KLGCVLYPDA CKRSPCQHGG SCTGLPSGGY QCTCLSQFTG RNCESEITAC FPNPCRNGGS CDPIGNTFIC NCKAGLTG
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 93%.
靶标信息
FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). The atypical cadherin Fat3 ensures that retinal amacrine cells (ACs) develop this unipolar morphology. Fat3 expression was restricted to the nervous system, for example in the brain, it is expressed in a variety of regions and axon fascicles. However, its strongest expression was observed in the olfactory bulb and retina.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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