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Proteintech
FBLIM1 Polyclonal Antibody
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产品信息
13349-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FBLIM1 Fusion Protein Ag3907 (1-373 aa encoded by BC019895)
偶联物
形式
Liquid
浓度
0.55 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is a rabbit polyclonal antibody raised against full length human FBLIM1 antigen.
Immunogen sequence: MASKPEKRV ASSVFITLAP PRRDVAVAEE VRQAVCEARR GRPWEAPAPM KTPEAGLAGR PSPWTTPGRA AATVPAAPMQ LFNGGCPPPP PVLDGEDVLP DLDLLPPPPP PPPVLLPSEE EAPAPMGASL IADLEQLHLS PPPPPPQAPA EGPSVQPGPL RPMEEELPPP PAEPVEKGAS TDICAFCHKT VFPRELAVEA MKRQYHAQCF TCRTCRRQLA GQSFYQKDGR PLCEPCYQDT LERCGKCGEV VRDHIIRALG QAFHPSCFTC VTCARCIGDE SFALGSQNEV YCLDDFYRKF APVCSICENP IIPRDGKDAF KIECMGRNFH ENCYRCEDCR ILLSVEPTDQ GCYPLNNHLF CKPCHVKRSA AGCC (1-373 aa encoded by BC019895)
靶标信息
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CSX-associated LIM; FBLP-1; Filamin-binding LIM protein 1; filamin-binding LIM protein-1; MIG2-interacting protein; Migfilin; mitogen-inducible 2 interacting protein; Mitogen-inducible 2-interacting protein
基因别名: CAL; FBLIM1; FBLP-1; FBLP1
UniProt ID: (Human) Q8WUP2
Entrez Gene ID: (Human) 54751
