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Proteintech
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This antibody recognizes isoform 1 (45 kDa) and isoform 3 (30-33 kDa).
Immunogen sequence: MADSETFIS LEECRGHKRA RKRTSMETAL ALEKLFPKQC QVLGIVTPGI VVTPMGSGSN RPQEIEIGES GFALLFPQIE GIKIQPFHFI KDPKNLTLER HQLTEVGLLD NPELRVVLVF GYNCCKVGAS NYLQQVVSTF SDMNIILAGG QVDNLSSLTS EKNPLDIDAS GVVGLSFSGH RIQSATVLLN EDVSDEKTAE AAMQRLKAAN IPEHNTIGFM FACVGRGFQY YRAKGNVEAD AFRKFFPSVP LFGFFGNGEI GCDRIVTGNF ILRKCNEVKD DDLFHSYTTI MALIHLGSSK (104-403 aa encoded by BC039024)
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Two transcript variants encoding different isoforms exist for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: F-box only protein 22; F-box protein FBX22p44; FIST domain containing 1
基因别名: FBX22; FBXO22; FISTC1
UniProt ID: (Human) Q8NEZ5
Entrez Gene ID: (Human) 26263