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Invitrogen
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PA1-4350 detects the FBG5 protein in human samples.
PA1-4350 has been successfully used in Western blot procedures.
The PA1-4350 immunizing peptide corresponds to amino acid residues 163-175 of the human FBG5 protein. There is 76% sequence identity to mouse.
F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。