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Abnova
FBXO33 Polyclonal Antibody, MaxPab™
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产品信息
H00254170-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FBXO33 (NP_976046.1, 1 a.a. approximately 555 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLLFLSVPQP RPPGARTRAG AARVARWRRL RLQQLRRLRG LLRVLRGRPG AGSRRRGRMA LCGQAAGAAS LPSELIVHIF SFLPAPDRLR ASASCSHWRE CLFYPALWPQ LRICLRVSPA EQPRLEFLMR KCGWFVRELR VEFAAENYLS GGGPGDGGGA DTGTGGEEVE ALQLSARWLE VLRTYLELVL CVLVSIRNNR NLQKFSLFGD ISVLQQQGSL SNTYLSKVDP DGKKIKQIQQ LFEEILSNSR QLKWLSCGFM LEIVTPTSLS SLSNAVANTM EHLSLLDNNI PGNSTLITAV ELERFVNLHS LALDFCDFTA EMARVLTDSN HVPLQRLSLL VHNVSVMHKS LDNMPNDEHW KALSRKSTSF RVYIMAFDIK SEDMLKILKP SIPLERIHFD SYITCVSGAI VDLISRQYDK FLTHFILMND VIDTSGFPDL SDNRNEDPLV LLAWRCTKLS LLAIHGYTVW AHNLIAIARL RGSDLKVLEV TEESIDFDQG ELADQDVDPV HNLIEQVSLG LGQPWHAVMD IESLSVFTEP NRHFYREMQS FSEDI
靶标信息
FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F-box only protein 33
基因别名: BMND12; c14_5247; FBX33; FBXO33
UniProt ID: (Human) Q7Z6M2
Entrez Gene ID: (Human) 254170
