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Invitrogen
FBXO4 Polyclonal Antibody
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FBXO4 Antibody (PA5-97311) in WB
Western blot analysis of FBXO4 in extracts of various cell lines. Samples were incubated with FBXO4 Polyclonal antibody (Product # PA5-97311) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.
产品信息
PA5-97311
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 138-387 of human FBXO4 (NP_0363081)
偶联物
形式
Liquid
浓度
1.12 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DYMAVYRMCC PYTRRASKSS RPMYGAVTSF LHSLIIQNEP RFAMFGPGLE ELNTSLVLSL MSSEELCPTA GLPQRQIDGI GSGVNFQLNN QHKFNILILY STTRKERDRA REEHTSAVNK MFSRHNEGDD QQGSRYSVIP QIQKVCEVVD GFIYVANAEA HKRHEWQDEF SHIMAMTDPA FGSSGRPLLV LSCISQGDVK RMPCFYLAHE LHLNLLNHPW LVQDTEAETL TGFLNGIEWI LEEVESKRAR; Positive Samples: SH-SY5Y, Mouse spleen, Mouse kidney, Mouse liver; Cellular Location: Cytoplasm
靶标信息
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F-box only protein 4; F-box protein Fbx4
基因别名: 1700096C12Rik; AI851261; AW494535; FBX4; FBXO4
UniProt ID: (Human) Q9UKT5, (Mouse) Q8CHQ0
Entrez Gene ID: (Human) 26272, (Mouse) 106052
