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Invitrogen
FCRL2 Polyclonal Antibody
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FCRL2 Antibody (PA5-80624) in WB
Western Blot using FCRL2 Polyclonal Antibody (Product # PA5-80624) at 1:500 dilution. Lane A: 293 Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary Goat Anti- RabbitIgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 56 kDa. Observed band size: 64 kDa. (We are unsure of the identity of these extra bands).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-80624
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human FCRL2/FcRH2 Protein (Met1-Asp395)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
5 mg/mL
规格
500 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human FCRL2/FcRH2.
靶标信息
The FCRL2 gene encodes the protein Fc receptor-like 2, which is part of the Fc receptor-like family involved in immune system regulation. FCRL2 is primarily expressed on the surface of B lymphocytes, where it contributes to the modulation of B cell activation and immune responses. As a member of the Fc receptor-like family, FCRL2 is thought to play roles in signaling pathways that influence B cell development, differentiation, and antibody production. It may act as a regulatory receptor that balances immune activation and inhibition, thereby contributing to immune homeostasis and prevention of autoimmunity. The expression of FCRL2 can impact conditions such as autoimmune diseases and B cell-related disorders, where dysregulation of B cell signaling is evident. Research into FCRL2 is ongoing to explore its specific ligand interactions and functional mechanisms, aiming to understand its potential as a therapeutic target for modulating immune responses in diseases characterized by B cell dysfunction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fc receptor homolog 2; IFGP family protein 4; Ig-like superfamily receptor; immune receptor translocation-associated protein 4; immunoglobulin receptor translocation-associated protein 4; immunoglobulin superfamily Fc receptor, gp42; IRTA4; FcRH2; membrane receptor; RP11-367J7.6; SH2 domain containing phosphatase anchor protein 1; SPAP1a; SPAP1b; SPAP1c; unnamed protein product
基因别名: CD307b; FCRH2; IFGP4; IRTA4; SPAP1; SPAP1A; SPAP1B; SPAP1C
UniProt ID: (Human) Q96LA5
Entrez Gene ID: (Human) 79368
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