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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Despite its predicted molecular weight, FEZ1 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is SK-N-SH cell lysate.
PA5-20396 can be used with blocking peptide PEP-0513.
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: F37; Fasciculation and elongation protein zeta-1; protein kinase C-binding protein Zeta1; zygin 1; Zygin I; Zygin-1
基因别名: Fez1; UNC-76; UNC76
UniProt ID: (Rat) P97577, (Mouse) Q8K0X8
Entrez Gene ID: (Rat) 81730, (Mouse) 235180