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Invitrogen
FGF8 Polyclonal Antibody
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FGF8 Antibody (PA5-47598) in IHC (P)
Immunohistochemical analysis of FGF8 in immersion fixed paraffin-embedded sections of human prostate. Samples were incubated in FGF8 polyclonal antibody (Product # PA5-47598) using a dilution of 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to epithelial and endothelial... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-47598
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant mouse FGF-8b Gln23-Arg215
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) FGF acidic, rhFGF basic, rhFGF-4, rhFGF-5, rhFGF-6, rhFGF-7 and rhFGF-9 is observed. This antibody will cross-react with recombinant mouse FGF-8c in neutralizing bioassay.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: androgen-induced; androgen-induced growth factor; FGF; Fibroblast growth factor; fibroblast growth factor 6c; heparin-binding growth factor 8; MGC149376; unnamed protein product
基因别名: Aigf; Fgf-8; Fgf6c; HBGF-8
UniProt ID: (Mouse) P37237
Entrez Gene ID: (Mouse) 14179
MAPK cascade
patterning of blood vessels
metanephros development
branching involved in ureteric bud morphogenesis
organ induction
kidney development
mesonephros development
neural plate morphogenesis
heart looping
blood vessel remodeling
heart morphogenesis
outflow tract septum morphogenesis
outflow tract morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
response to oxidative stress
determination of left/right symmetry
heart development
motor neuron axon guidance
mesodermal cell migration
positive regulation of cell proliferation
gonad development
fibroblast growth factor receptor signaling pathway
response to xenobiotic stimulus
embryo development ending in birth or egg hatching
dorsal/ventral pattern formation
positive regulation of gene expression
telencephalon development
pallium development
subpallium development
forebrain dorsal/ventral pattern formation
cell proliferation in forebrain
forebrain neuron development
central nervous system neuron development
neurogenesis
signal transduction involved in regulation of gene expression
lung development
regulation of cell migration
male genitalia development
thyroid gland development
otic vesicle formation
midbrain-hindbrain boundary development
dorsal/ventral axon guidance
embryonic heart tube development
limb morphogenesis
embryonic hindlimb morphogenesis
aorta morphogenesis
inner ear morphogenesis
odontogenesis
regulation of odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
cell fate commitment
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of mitotic nuclear division
positive regulation of organ growth
generation of neurons
embryonic neurocranium morphogenesis
forebrain morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
negative regulation of cardiac muscle tissue development
pharyngeal system development
corticotropin hormone secreting cell differentiation
thyroid-stimulating hormone-secreting cell differentiation
bone development
lung morphogenesis
branching involved in salivary gland morphogenesis
neuroepithelial cell differentiation
positive regulation of ERK1 and ERK2 cascade
dopaminergic neuron differentiation
cell migration involved in mesendoderm migration
larynx morphogenesis
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