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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MSAGEVERL VSELSGGTGG DEEEEWLYGD ENEVERPEEE NASANPPSGI EDETAENGVP KPKVTETEDD SDSDSDDDED DVHVTIGDIK TGAPQYGSYG TAPVNLNIKT GGRVYGTTGT KVKGVDLDAP GSINGVPLLE VDLDSFEDKP WRKPGADLSD YFNYGFNEDT WKAYCEKQKR IRMGLEVIPV TSTTNKITAE DCTMEVTPGA EIQDGRFNLF KVQQGRTGNS EKETALPSTK AEFTSPPSLF KTGLPPSRNS TSSQSQTSTA SRKANSSVGK WQDRYGRAES PDLRRLPGAI DVIGQTITIS RVEGRRRANE NSNIQVLSER SATEVDNNFS KPPPFFPPGA P (1-350 aa encoded by BC017724)
FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp586K0717; factor interacting with PAP; FIP1 like 1; FIP1-like 1 protein; FIP1L1 cleavage and polyadenylation specific factor subunit; FLJ33619; rearranged in hypereosinophilia; unnamed protein product
基因别名: 1300019H17Rik; FIP1; hFip1; Rhe; Rje
UniProt ID: (Human) Q6UN15, (Rat) Q5U317, (Mouse) Q9D824
Entrez Gene ID: (Human) 81608, (Rat) 289582, (Mouse) 66899