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Invitrogen
FMNL1 Polyclonal Antibody
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FMNL1 Antibody (PA5-88912) in WB
Western blot analysis of FMNL1 in extracts of various cell lines. Samples were incubated with FMNL1 Polyclonal antibody (Product # PA5-88912) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88912
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_0058832)
偶联物
形式
Liquid
浓度
2.78 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DLHFLDKAGS VSLDSVLADV RSLQRGLELT QREFVRQDDC MVLKEFLRAN SPTMDKLLAD SKTAQEAFES VVEYFGENPK TTSPGLFFSL FSRFIKAYKK AEQEVEQWKK EAAAQEAGAD TPGKGEPPAP KSPPKARRPQ MDLISELKRR QQKEPLIYES DRDGAIEDII T; Positive Samples: LO2, A-549, Mouse brain; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Lipid-anchor, bleb, cell cortex, phagosome
靶标信息
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CLL-associated antigen KW-13; formin-like 1; Formin-like protein 1; formin-related gene in leukocytes; Formin-related protein; Leukocyte formin; lymphocyte specific formin related protein
基因别名: 8030453N10Rik; AI553564; C17orf1; C17orf1B; FHOD4; FMNL; FMNL1; Fnrl; Frl; FRL1; Frls; KW-13
UniProt ID: (Human) O95466, (Mouse) Q9JL26
Entrez Gene ID: (Human) 752, (Mouse) 57778
