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Invitrogen
FOLR4 Polyclonal Antibody
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产品信息
PA5-44954
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human FOLR4
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: TCKSNWRGGW DWSQGKNRCP KGAQCLPFSH YFPTPADLCE KTWSNSFKAS
Sequence homology: Guinea Pig: 85%; Horse: 90%; Human: 100%
靶标信息
FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Folate receptor 4; folate receptor 4 (delta) homolog; folate receptor 4, delta (putative); Folate receptor delta; FR-delta; IZUMO1 receptor protein JUNO; probable folate receptor delta; Sperm-egg fusion protein Juno
基因别名: Folbp3; FOLR4; IZUMO1R; JUNO
UniProt ID: (Human) A6ND01
Entrez Gene ID: (Human) 390243
