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Proteintech
FOXM1 Polyclonal Antibody
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产品信息
13147-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FOXM1 Fusion Protein Ag3729 (445-748 aa encoded by BC006192)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Product # 13147-1-AP is rabbit polyclonal antibody raised against C-terminal of human FOXM1. This antibody can recognize three kinds of FOXM1,FOXM1-pp (~95-110 kDa), FOXM1-B (isoform2,~83 kDa) and FOXM1A (isoform4, ~90 kDa)
Immunogen sequence: KEEEIQPGE EMPHLARPIK VESPPLEEWP SPAPSFKEES SHSWEDSSQS PTPRPKKSYS GLRSPTRCVS EMLVIQHRER RERSRSRRKQ HLLPPCVDEP ELLFSEGPST SRWAAELPFP ADSSDPASQL SYSQEVGGPF KTPIKETLPI SSTPSKSVLP RTPESWRLTP PAKVGGLDFS PVQTPQGASD PLPDPLGLMD LSTTPLQSAP PLESPQRLLS SEPLDLISVP FGNSSPSDID VPKPGSPEPQ VSGLAANRSL TEGLVLDTMN DSLSKILLDI SFPGLDEDPL GPDNINWSQF IPELQ (445-748 aa encoded by BC006192)
靶标信息
FOXM1 (forkhead box protein M1) is a transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. FOXM1 plays a role in the control of cell proliferation and DNA break repairs participating in the DNA damage checkpoint response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FKH L16; FKHL 16; Forkhead box protein M1; forkhead homolog 16; Forkhead like 16; Forkhead, drosophila, homolog-like 16; Forkhead-related protein FKHL16; FOXM 1; FOXM 1c; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH 11; HFH-11; HNF 3; HNF-3/fork-head homolog 11; HNF3; INS 1; INS1; M-phase phosphoprotein 2; MPHOSPH 2; MPM 2; MPM-2 reactive phosphoprotein 2; MPP 2; PIG 29; TGT3; Transcription factor Trident; trident; Winged-helix factor from INS-1 cells; winged-helix transcription factor Trident
基因别名: AA408308; AW554517; BB238854; Fkh16; FKHL16; FOXM1; FOXM1B; HFH-11; HFH-11B; HFH11; HNF-3; INS-1; MPHOSPH2; Mpm2; MPP-2; MPP2; PIG29; TRIDENT; WIN
UniProt ID: (Human) Q08050
Entrez Gene ID: (Human) 2305, (Mouse) 14235
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
liver development
DNA repair
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
cell cycle
positive regulation of cell proliferation
anatomical structure morphogenesis
negative regulation of stress-activated MAPK cascade
regulation of cell proliferation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of Ras protein signal transduction
regulation of cell cycle arrest
negative regulation of cell aging
regulation of reactive oxygen species metabolic process
positive regulation of double-strand break repair
response to gonadotropin
response to cAMP
regulation of cell cycle
