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Invitrogen
FOXM1 Monoclonal Antibody (CL12131)
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FOXM1 Antibody (MA5-44163) in ICC/IF
Immunofluorecent analysis of FOXM1 in U-251 MG cells using FOXM1 Monoclonal Antibody (CL12131) (Product # MA5-44163). Staining shows specific staining in nuclear speckles and nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-44163
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CL12131
抗原
Recombinant protein corresponding to Human FOXM1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody solution should be gently mixed before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: ARPIKVESPP LEEWPSPA
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.
靶标信息
FOXM1 (forkhead box protein M1) is a transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. FOXM1 plays a role in the control of cell proliferation and DNA break repairs participating in the DNA damage checkpoint response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell proliferation-inducing gene 29 protein; FKH L16; FKHL 16; forkhead box M1-D; Forkhead like 16; Forkhead, drosophila, homolog-like 16; forkhead-related protein FKHL16; FOXM 1; FOXM 1c; hepatocyte nuclear factor 3 forkhead homolog 11; hepatocyte nuclear factor-3/fork head homolog 11A; winged helix transcription factor; HFH 11; HNF 3; HNF-3/fork-head homolog 11; HNF3; INS 1; INS1; M-phase phosphoprotein 2; MPHOSPH 2; MPM 2; MPM-2 reactive phosphoprotein 2; MPP 2; PIG 29; TGT3; transcription factor Trident; unnamed protein product; winged helix transcription factor; hepatocyte nuclear factor-3/fork head homolog 11B; winged-helix factor from INS-1 cells
基因别名: FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT
UniProt ID: (Human) Q08050
Entrez Gene ID: (Human) 2305
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein kinase binding
phosphatidylinositol 3-kinase regulatory subunit binding
phosphatidylinositol 3-kinase catalytic subunit binding
sequence-specific DNA binding
protein serine/threonine kinase binding
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of mitotic cell cycle
positive regulation of cell proliferation
positive regulation of epithelial to mesenchymal transition
DNA damage response, signal transduction by p53 class mediator
negative regulation of stress-activated MAPK cascade
regulation of cell proliferation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of Ras protein signal transduction
regulation of cell cycle
regulation of reactive oxygen species metabolic process
positive regulation of double-strand break repair
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