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Invitrogen
FOXP1 Recombinant Rabbit Monoclonal Antibody (RM402)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-36069
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
RM402
抗原
A peptide corresponding to residues near the C-terminus of human Foxp1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.02 mg/mL
规格
2 µg
纯化类型
Protein A
保存液
PBS with 50% glycerol, 1% BSA
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody may also react to mouse or rat Foxp1, as predicted by immunogen homology.
靶标信息
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ23741; Fork head related protein like B; fork head-related protein like B; Forkhead box protein P1 (FOXP1); FOXP1; Glutamine rich factor 1; glutamine-rich factor 1; mac-1-regulated forkhead; MGC12942; MGC88572; MGC99551; unnamed protein product
基因别名: 12CC4; hFKH1B; HSPC215; MFH; QRF1
UniProt ID: (Human) Q9H334
Entrez Gene ID: (Human) 27086
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
androgen receptor binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
negative regulation of B cell apoptotic process
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
regulation of gene expression
positive regulation of endothelial cell migration
negative regulation of gene expression
striatum development
osteoclast differentiation
forebrain development
response to lipopolysaccharide
regulation of interleukin-1 beta production
regulation of interleukin-12 production
regulation of tumor necrosis factor production
positive regulation of interleukin-21 production
response to testosterone
osteoclast development
macrophage activation
monocyte activation
endothelial cell activation
regulation of monocyte differentiation
negative regulation of transcription, DNA-templated
animal organ development
positive regulation of smooth muscle cell proliferation
regulation of inflammatory response
positive regulation of B cell receptor signaling pathway
negative regulation of androgen receptor signaling pathway
negative regulation of cell growth involved in cardiac muscle cell development
T follicular helper cell differentiation
cellular response to tumor necrosis factor
regulation of defense response to bacterium
regulation of macrophage colony-stimulating factor production
positive regulation of hydrogen peroxide-mediated programmed cell death
regulation of endothelial tube morphogenesis
regulation of chemokine (C-X-C motif) ligand 2 production
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