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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (92%), Rat (92%), Xenopus laevis (81%), Chicken (84%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 3-dehydrosphinganine reductase; 3-ketodihydrosphingosine reductase; Follicular variant translocation protein 1; FVT-1; KDS reductase; Short chain dehydrogenase/reductase family 35C member 1
基因别名: FVT1; KDSR; SDR35C1
Entrez Gene ID: (Human) 2531