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Invitrogen
FZR1 Polyclonal Antibody
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FZR1 Antibody (PA5-85303) in ICC/IF
Immunocytochemistry analysis of FZR1 in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Samples were incubated with FZR1 polyclonal antibody (Product # PA5-85303) using a dilution of 1:500 (green). Red: Phalloidin, a cytoskeleton marker, diluted at 1:100. Scale bar = 10 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-85303
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human FZR1. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.26 mg/mL
规格
26 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (95%), Rat (95%), Xenopus laevis (90%), Pig (97%), Chicken (94%), Rhesus Monkey (100%), Bovine (97%).
Positive Control: A431, A431 nuclear extract.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
FZR is a 7WD domain family member implicated in cell cycle regulation of Drosophila and yeast. It has been shown that the over expression of fzr proteins increases natural killer cell-mediated cell death and as a result, suppresses tumor growth. The fzr protein is essential for cyclosome activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: APC regulator; CDC20 homolog 1; CDC20-like 1b; CDC20-like protein 1; CDH1; cdh1/Hct1 homolog; cell division cycle 20 related 1; fizzy/cell division cycle 20 related 1; unnamed protein product
基因别名: CDC20C; CDH1; DEE109; Fyr; FZR; FZR2; HCDH; HCDH1
UniProt ID: (Human) Q9UM11, (Mouse) Q9R1K5
Entrez Gene ID: (Human) 51343, (Mouse) 56371, (Rat) 314642
mitotic G2 DNA damage checkpoint
positive regulation of cell proliferation
protein ubiquitination
protein catabolic process
anaphase-promoting complex-dependent catabolic process
regulation of meiotic nuclear division
thymidine biosynthetic process
lens fiber cell differentiation
positive regulation of ubiquitin protein ligase activity
DNA synthesis involved in mitotic DNA replication
positive regulation of anaphase-promoting complex-dependent catabolic process
negative regulation of cellular senescence
negative regulation of meiotic cell cycle process involved in oocyte maturation
regulation of mitotic cell cycle
regulation of meiotic cell cycle
protein K11-linked ubiquitination
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