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Abnova
FZR1 Monoclonal Antibody (3E12)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00051343-M09
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3E12
抗原
FZR1 (NP_057347.2, 1 a.a. approximately 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.47 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MDQDYERRLL RQIVIQNENT MPRVTEMRRT LTPASSPVSS PSKHGDRFIP SRAGANWSVN FHRINENEKS PSQNRKAKDA TSDNGKDGLA YSALLKNELL G
靶标信息
FZR is a 7WD domain family member implicated in cell cycle regulation of Drosophila and yeast. It has been shown that the over expression of fzr proteins increases natural killer cell-mediated cell death and as a result, suppresses tumor growth. The fzr protein is essential for cyclosome activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: APC regulator; CDC20 homolog 1; CDC20-like 1b; CDC20-like protein 1; CDH1; cdh1/Hct1 homolog; fizzy/cell division cycle 20 related 1
基因别名: CDC20C; CDH1; DEE109; FZR; FZR2; HCDH; HCDH1
UniProt ID: (Human) Q9UM11
Entrez Gene ID: (Human) 51343
mitotic G2 DNA damage checkpoint
regulation of mitotic cell cycle
positive regulation of cell proliferation
protein ubiquitination
anaphase-promoting complex-dependent catabolic process
regulation of meiotic cell cycle
protein K11-linked ubiquitination
positive regulation of ubiquitin protein ligase activity
positive regulation of anaphase-promoting complex-dependent catabolic process
negative regulation of cellular senescence
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