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Invitrogen
Factor XI Polyclonal Antibody, Biotin
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产品信息
PA1-74028
产品规格
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Factor XI from human plasma.
偶联物
形式
Liquid
保存条件
4°C
运输条件
Wet ice
产品详细信息
PA1-74028 detects Factor XI from human samples.
PA1-74028 has been successfully used in ELISA and immunoelectrophoresis applications.
The PA1-74028 immunogen is Factor XI from human plasma.
靶标信息
This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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