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Invitrogen
Ferroportin Polyclonal Antibody
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FIGURE: 1 / 13
Ferroportin Antibody (PA5-22993) in ICC/IF
Immunocytochemistry analysis of Ferroportin in HepG2 cells. Samples were incubated with Ferroportin polyclonal antibody (Product # PA5-22993) using a dilution of 5.0 µg/mL overnight at 4°C followed by anti-rabbit DyLight 488 (green) at a dilution of 1:500. Cells were fixed and permeabilized for 10 minutes using -20°C MeOH. Alpha tubulin (DM1A) was used as a co-stain at a 1:1,000 dilution and detected with a... View More
Product Details
PA5-22993
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Pig,
Rat
Published species
C. elegans,
Human,
Mouse,
Rhesus monkey
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide made to an internal portion of human Ferroportin 1 (within residues 250-300).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Suggested positive control: human intestine protein.
Target Information
SLC40A1 is an iron-regulated transporter assumed to play roles in intestinal iron absorption and cellular iron release. It mediates iron efflux in the presence of ferroxidase. Defects in SLC40A1 cause hemochromatosis type 4 (HFE4), which is an autosomal dominant iron-loading disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CAR1; Cell adhesion regulator; duodenal-specific; Ferroportin; ferroportin 1; Ferroportin-1; iron regulated gene 1; Iron-regulated transporter 1; Metal transporter protein 1; metal transporting protein 1; MTP1; polycythaemia; SLC11A3 iron transporter; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 (iron-regulated transporter), member 1; Solute carrier family 40 member 1
Gene Aliases: Dusg; FPN; FPN1; Fpt1; HFE4; IREG1; MST079; MSTP079; MTP; MTP1; Ol5; Pcm; SLC11A3; Slc39a1; SLC40A1
UniProt ID: (Human) Q9NP59, (Mouse) Q9JHI9, (Rat) Q923U9
Entrez Gene ID: (Bovine) 527023, (Human) 30061, (Pig) 100737517, (Mouse) 53945, (Rat) 170840
lymphocyte homeostasis
endothelium development
cellular iron ion homeostasis
regulation of transcription from RNA polymerase II promoter in response to iron
iron ion transmembrane transport
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
spleen trabecula formation
multicellular organismal iron ion homeostasis
ferrous iron export
transport
ion transport
iron ion transport
spleen development
iron ion homeostasis
ferrous iron transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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