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Invitrogen
Fibrillin 1 Monoclonal Antibody (11C1.3)
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Fibrillin 1 Antibody (MA5-12770) in ICC/IF
Immunofluorescence analysis of Fibrillin-1 was performed using 70% confluent log phase SH-SY5Y cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Fibrillin-1 (11C1.3) Mouse Monoclonal Antibody (Product # MA5-12770) at 2µg/mL in 0.1% BSA and incubated for... View More
产品信息
MA5-12770
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human,
Pig
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
11C1.3
抗原
Microfibrils from zonular apparatus of bovine eye
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-12770 targets Fibrillin-1 in ICC/IF, IHC (F), IM, and WB applications and shows reactivity with Bovine and Human samples.
The MA5-12770 immunogen is microfibrils from zonular apparatus of bovine eye.
靶标信息
Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. Fibrillin 1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in Fibrillin 2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
