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Fleroxacin is a second-generation broad-spectrum fluoroquinolone antibiotic, distinguished by its trifluorinated structure, which sets it apart from other fluoroquinolones like ciprofloxacin and ofloxacin. Its gene location and structure are not typically discussed in the context of biosimilars, as fleroxacin itself is a chemical compound rather than a biologic entity. Fleroxacin's long half-life allows for once-daily dosing, enhancing patient compliance. It has been investigated for its potential repositioning from an antibiotic to an anti-cancer agent, showing potentiating effects when combined with known anticancer drugs such as 5-fluorouracil against bladder cancer cells. The development and use of biosimilars in clinical practice aim to improve patient accessibility to modern medicines, providing similar efficacy and safety parameters as their reference drugs. Fleroxacin's improved photostability, solubility, and antimicrobial activity have been achieved through the synthesis of pharmaceutical salts, such as fleroxacin-D-tartaric acid, enhancing its therapeutic potential.
仅用于科研。不用于诊断过程。未经明确授权不得转售。