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Invitrogen
FosB Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-148574
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant human FosB, Met1-Leu338
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
c-FOS is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It has a critical function in regulating the development of cells destined to form and maintain the skeleton, and is thought to have an important role in signal transduction, cell proliferation and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activator protein 1; DKFZp686C0818; FBJ murine osteosarcoma viral oncogene homolog B; fos b; FOSB; FosB proto-oncogene, AP-1 trancription factor subunit; G0/G1 switch regulatory protein 3; GOS3 is human homolog of mouse FOSB gene; MGC42291; oncogene FOS-B; transcription factor AP-1 subunit FosB; unnamed protein product
基因别名: AP-1; G0S3; GOS3; GOSB
UniProt ID: (Human) P53539
Entrez Gene ID: (Human) 2354
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
response to amphetamine
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
female pregnancy
response to xenobiotic stimulus
response to mechanical stimulus
response to progesterone
cellular response to hormone stimulus
response to nicotine
response to cocaine
response to morphine
response to ethanol
positive regulation of transcription from RNA polymerase II promoter
behavioral response to cocaine
response to corticosterone
response to cAMP
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