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Invitrogen
Fractin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-95652
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acid residues from the C terminal region of the 32-kDa actin fragment
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
Conc. Not Determined
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is specific for endogenous levels of the ~32 kDa fractin protein and shows no reactivity toward intact actin. There is often a ladder of smaller bands in cells or culture or in-vivo preparations due to further degradation by other proteases. In IHC, the antibody detects the processes and cell bodies of degenerating neurons and plaque-associated microglia in Alzheimer's disease.
靶标信息
Fractin (fragment of actin) is a caspase-specific cleavage product of actin and serves as a novel marker of apoptosis-related events. It has recently been reported that fractin may have a functional role in apoptotic signaling in oligodendrocytes (Schulz, R., et al., Glia, 2009).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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