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Agrisera
FtsH9/ATP-dependent zinc metalloprotease FtsH9 (chloroplastic) Polyclonal Antibody
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产品信息
AS06-130
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated synthetic peptide derived from Arabidopsis thaliana FtsH9 protein sequence.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
规格
400 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 182 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
FtsH9 encodes a chloroplast-targeted, membrane-anchored AAA+ metalloprotease that localizes predominantly to the chloroplast envelope. It is synthesized as a nuclear-encoded precursor with an N-terminal chloroplast transit peptide, followed by one or more N-terminal transmembrane helices that anchor the protein in the envelope and position a large stromal-facing catalytic region. The mature protein is a member of the M41 FtsH family and is characterized by a central AAA+ ATPase module (with conserved Walker motifs required for ATP-dependent substrate engagement/unfolding) coupled to a C-terminal Zn2+-dependent protease domain containing the canonical HEXXH metal-binding motif. Comparative analyses of Arabidopsis plastid FtsH proteases indicate that, unlike the abundant thylakoid FtsH complexes primarily implicated in photosystem II repair, FtsH9 belongs to an envelope-associated subgroup (including FtsH7/9/12 and related inactive FtsHi proteins), and its specific in vivo substrates and physiological role remain incompletely defined; nonetheless, its domain architecture strongly supports a role in ATP-dependent quality control and/or regulated turnover of chloroplast envelope proteins, contributing to proteostasis at the organelle boundary.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: At5g58870; AtFTSH9; FTSH9; K19M22.7
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