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Invitrogen
GABBR2 Polyclonal Antibody
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GABBR2 Antibody (PA5-28340) in IHC (F)
Immunohistochemistry (Frozen) analysis of GABBR2 was performed in frozen sectioned E13.5 Rat brain tissue using GABBR2 Polyclonal Antibody (Product # PA5-28340) at a dilution of 1:250 (Green). Red: beta Tubulin 3/ TUJ1, a mature neuron marker, stained by beta Tubulin 3/ TUJ1 antibody diluted at 1:500. Blue: Fluoroshield with DAPI.
产品信息
PA5-28340
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 163 and 516 of Human GABA B Receptor 2
偶联物
形式
Liquid
浓度
0.83 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: U87-MG, unboiled Myc-DDK-tagged Gabbr2-transfected 293T.
Predicted reactivity: Mouse (97%), Rat (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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