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Invitrogen
GABRA4 Polyclonal Antibody
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产品信息
PA5-95654
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Fusion protein from the cytoplasmic loop of the alpha 4 subunit
偶联物
形式
Liquid
浓度
0.15 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
靶标信息
Gamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1. Alternatively spliced transcript variants encoding different isoforms have been found in this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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