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Proteintech
GAS1 Polyclonal Antibody
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产品信息
17903-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GAS1 Fusion Protein Ag12275 (28-345 aa encoded by BC074908)
偶联物
形式
Liquid
浓度
0.39 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LQLLGSAPR GSGLAHGRRL ICWQALLQCQ GEPECSYAYN QYAEACAPVL AQHGGGDAPG AAAAAFPASA ASFSSRWRCP SHCISALIQL NHTRRGPALE DCDCAQDENC KSTKRAIEPC LPRTSGGGAG GPGAGGVMGC TEARRRCDRD SRCNLALSRY LTYCGKVFNG LRCTDECRTV IEDMLAMPKA ALLNDCVCDG LERPICESVK ENMARLCFGA ELGNGPGSSG SDGGLDDYYD EDYDDEQRTG GAGGEQPLDD DDGVPHPPRP GSGAAASGGR GDLPYGPGRR SSGGGGRLAP RGAWTPLASI LLLLLGPLF (28-345 aa encoded by BC074908)
靶标信息
Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GAS-1; growth arrest-specific 1; Growth arrest-specific gene-1; Growth arrest-specific protein 1
基因别名: AW554192; Gas-1; GAS1
UniProt ID: (Human) P54826, (Mouse) Q01721
Entrez Gene ID: (Human) 2619, (Mouse) 14451
cell cycle arrest
regulation of smoothened signaling pathway
negative regulation of protein processing
cellular response to vascular endothelial growth factor stimulus
regulation of apoptotic process
cell fate commitment
negative regulation of mitotic cell cycle
developmental growth
regulation of ER to Golgi vesicle-mediated transport
positive regulation of mesenchymal cell proliferation
cell cycle
axon guidance
positive regulation of cell proliferation
dorsal/ventral pattern formation
programmed cell death
cerebellum morphogenesis
dorsal/ventral neural tube patterning
negative regulation of cell growth
outer ear morphogenesis
middle ear morphogenesis
odontogenesis
embryonic digit morphogenesis
camera-type eye development
negative regulation of apoptotic process
negative regulation of smoothened signaling pathway
positive regulation of smoothened signaling pathway
eye morphogenesis
embryonic morphogenesis
embryonic cranial skeleton morphogenesis
embryonic skeletal system development
positive regulation of epithelial cell proliferation
negative regulation of epithelial cell proliferation
palate development
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
