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OriGene
GBA3 Monoclonal Antibody (OTI3E8), TrueMAB™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
CF502516
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI3E8
抗原
Human recombinant protein fragment corresponding to amino acids 1-150 and 370-469 of human GBA3 produced in E.coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides. GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytosolic beta-glucosidase-like protein 1; cytosolic galactosylceramidase; cytosolic GCase; cytosolic glucosylceramidase; cytosolic glycosylceramidase; glucosidase beta acid 3; glucosidase, beta, acid 3 (cytosolic); glycosyl hydrolase; klotho-related protein; unnamed protein product
基因别名: CBG; CBGL1; GLUC; KLRP
UniProt ID: (Human) Q9H227
Entrez Gene ID: (Human) 57733
carbohydrate metabolic process
glucosylceramide catabolic process
galactosylceramide catabolic process
oligosaccharide catabolic process
carbohydrate catabolic process
glycoside catabolic process
glycosylceramide catabolic process
glycosphingolipid catabolic process
protein stabilization
beta-glucoside catabolic process
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
