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Invitrogen
GCAP2 Polyclonal Antibody
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产品信息
PA5-56751
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human GCAP2
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: QLKKACRREL QTEQGQLLTP EEVVDRIFLL VDENGDGQLS LNEFVEGARR DKWVMKMLQM DMNPSSWLAQ QRRK
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.
靶标信息
Guanylate cyclase-activating proteins (GCAPs) are calcium binding proteins that belong to the calmodulin superfamily. GCAPs without calcium are responsible for activation of photoreceptor guanylate cyclase during light adaptation. Studies have shown that the addition or subtraction of Ca2+ results in major conformational changes and the activation/deactivation of GCAP-1 and GCAP-2. It has been demonstrated that both GCAP-1 and 2 act on guanylate cyclase similarly and have approximately 50% homology between the two forms. GCAP-1 is predominantly localized in the photoreceptor outer segments, while GCAP-2 is found in retina samples.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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