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Invitrogen
GCNF Polyclonal Antibody
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产品信息
PA5-34020
产品规格
种属反应
Bat,
Bovine,
Dog,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 18 amino acid peptide from ligand-binding domain of human NR6A1 / GCNF.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GCNF; Germ cell nuclear factor; germ cell nuclear factor variant 1; h hRTR; mGCNF; nuclear receptor subfamily 5, group A, member 1; Nuclear receptor subfamily 6 group A member 1; nuclear receptor subfamily 6, group A, member 1; retinoic acid receptor-related testis-associated receptor; Retinoid receptor-related testis-specific receptor; RTR; steroidogenic factor 1
基因别名: 1700113M01Rik; CT150; GCNF; GCNF1; hGCNF; hRTR; I79_020174; NCNF; NR5A1; NR61; NR6A1; RTR; Sf1
UniProt ID: (Human) Q8NHQ0, (Pig) A0P8Z4, (Mouse) Q64249
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
zinc ion binding
protein homodimerization activity
sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
metal ion binding
C4 zinc finger nuclear receptor
negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
gamete generation
spermatogenesis
cell proliferation
intracellular steroid hormone receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
multicellular organism development
cell differentiation
transcription, DNA-templated
transcription from RNA polymerase II promoter
steroid hormone mediated signaling pathway
