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Proteintech
GCNT2 Polyclonal Antibody
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产品信息
18118-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GCNT2 Fusion Protein Ag12635 (29-400 aa encoded by BC074801)
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: GDPSFQRLN ISDPLRLTQV CTSFINGKTR FLWKNKLMIH EKSSCKEYLT QSHYITAPLS KEEADFPLAY IMVIHHHFDT FARLFRAIYM PQNIYCVHVD EKATTEFKDA VEQLLSCFPN AFLASKMEPV VYGGISRLQA DLNCIRDLSA FEVSWKYVIN TCGQDFPLKT NKEIVQYLKG FKGKNITPGV LPPAHAIGRT KYVHQEHLGK ELSYVIRTTA LKPPPPHNLT IYFGSAYVAL SREFANFVLH DPRAVDLLQW SKDTFSPDEH FWVTLNRIPG VPGSMPNASW TGNLRAIKWS DMEDRHGGCH GHYVHGICIY GNGDLKWLVN SPSLFANKFE LNTYPLTVEC LELRHRERTL NQSETAIQPS WYF (29-400 aa encoded by BC074801)
靶标信息
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1, 6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: beta-1,6-N-acetylglucosaminyltransferase; beta-1,6-N-acetylglucosaminyltransferase 2; glucosaminyltransferase, I-branching enzyme; I beta-1,6-N-acetylglucosaminyltransferase; I-branching beta-1,6-acetylglucosaminyltransferase; I-branching enzyme; IGNT; Ii blood group; Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase; N-acetylglucosaminyltransferase; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase
基因别名: 5330430K10Rik; bA360O19.2; bA421M1.1; CCAT; CTRCT13; GCNT2; GCNT2C; GCNT5; IGNT; IGnTA; IGnTB; IGnTC; II; NACGT1; NAGCT1; ULG3
UniProt ID: (Human) Q8N0V5, (Mouse) P97402
Entrez Gene ID: (Human) 2651, (Rat) 306860, (Mouse) 14538
glycosaminoglycan biosynthetic process
protein glycosylation
transforming growth factor beta receptor signaling pathway
multicellular organism development
positive regulation of cell proliferation
posttranscriptional regulation of gene expression
positive regulation of epithelial to mesenchymal transition
negative regulation of cell-substrate adhesion
positive regulation of cell migration
positive regulation of heterotypic cell-cell adhesion
maintenance of lens transparency
positive regulation of protein kinase B signaling
positive regulation of ERK1 and ERK2 cascade
biological_process
metabolic process
