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Invitrogen
GCNT2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-98712
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase protein (203-402AA)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.53 mg/mL
规格
53 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1, 6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AIGnT; beta-1,6-N-acetylglucosaminyltransferase; beta-1,6-N-acetylglucosaminyltransferase 2; beta6 GlcNAc-T; BIGnT; CIGnT; glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group); glucosaminyltransferase, I-branching enzyme; I beta-1,6-N-acetylglucosaminyltransferase; I-branching enzyme; IGNT; IGNT1; IGNT2; IGNT3; Ii blood group; Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase; N-acetylglucosaminyltransferase; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase; unnamed protein product
基因别名: 5330430K10Rik; bA360O19.2; bA421M1.1; CCAT; CTRCT13; GCNT2; GCNT2C; GCNT5; IGNT; IGnTA; IGnTB; IGnTC; II; NACGT1; NAGCT1; ULG3
UniProt ID: (Mouse) P97402
Entrez Gene ID: (Human) 2651, (Mouse) 14538
glycosaminoglycan biosynthetic process
transforming growth factor beta receptor signaling pathway
multicellular organism development
positive regulation of cell proliferation
glycoprotein biosynthetic process
posttranscriptional regulation of gene expression
positive regulation of epithelial to mesenchymal transition
negative regulation of cell-substrate adhesion
positive regulation of cell migration
positive regulation of heterotypic cell-cell adhesion
maintenance of lens transparency
positive regulation of protein kinase B signaling
positive regulation of ERK1 and ERK2 cascade
protein glycosylation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
