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Proteintech
GFM2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
16941-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GFM2 Fusion Protein Ag10530 (430-779 aa encoded by BC015712)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.13 mg/mL
规格
19.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: GNIALTVGL KHTATGDTIV SSKSSALAAA RRAEREGEKK HRQNNEAERL LLAGVEIPEP VFFCTIEPPS LSKQPDLEHA LKCLQREDPS LKVRLDPDSG QTVLCGMGEL HIEIIHDRIK REYGLETYLG PLQVAYRETI LNSVRATDTL DRTLGDKRHL VTVEVEARPI ETSSVMPVIE FEYAESINEG LLKVSQEAIE NGIHSACLQG PLLGSPIQDV AITLHSLTIH PGTSTTMISA CVSRCVQKAL KKADKQVLEP LMNLEVTVAR DYLSPVLADL AQRRGNIQEI QTRQDNKVVI GFVPLAEIMG YSTVLRTLTS GSATFALELS TYQAMNPQDQ NTLLNRRSGL T (430-779 aa encoded by BC015712)
靶标信息
GFM2 is involved in mitochondrial translation, which is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. In Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: G elongation factor; G elongation factor mitochondrial 2; hEFG2; mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; mitochondrial ribosome-releasing factor 2; ribosome releasing factor 2; unnamed protein product
基因别名: EF-G2mt; EFG2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF; RRF2; RRF2mt
UniProt ID: (Human) Q969S9
Entrez Gene ID: (Human) 84340
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