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Invitrogen
GKN1 Polyclonal Antibody
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GKN1 Antibody (PA5-23309) in WB
Western blot analysis of GKN1 in human stomach tissue lysate. Samples were incubated in GKN1 polyclonal antibody (Product # PA5-23309) using a dilution of 1.0 µg/mL, 1.0 µg/mL and 0.5 µg/mL, respectively followed by a goat anti-rabbit Ig HRP secondary antibody. PicoTect ECL substrate solution was used for this test.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-23309
产品规格
种属反应
Horse,
Human,
Non-human primate,
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
The portions of amino acids range between 100-150 of human GKN1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The amino acid sequence used as immunogen is 100% homologous in chimpanzee and dog, 94% homologous in mouse and cow, 88% homologous in rat and 77% homologous in chicken.
靶标信息
Gastrokine 1, also known as GKN1 and CA11, is a 185 amino acid containing secreted protein belonging to the gastrokine family with a BRICHOS domain and an asn-rich region. GKN1 (also known as an antioncogene) is reported to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. Differential display of normal and cancerous gastric tissue suggested that this protein is predominantly expressed in stomach and the expression is down-regulated to considerable frequency in cancer tissue or gastric cancer cell lines examined. This extra cellular protein is co-secreted with mucins and is a signaling growth factor with mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 18 kDa antrum mucosa protein; AMP-18; Amp18; gastrokine; Gastrokine-1
基因别名: AMP-18; AMP18; GKN1
UniProt ID: (Pig) Q8HYA9
Entrez Gene ID: (Pig) 100502561, (Horse) 100061374
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