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Invitrogen
GLAST Polyclonal Antibody
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GLAST Antibody (PA5-80012) in WB
Western blot was performed using GLAST Polyclonal Antibody (Product # PA5-80012) and a 55 kDa band corresponding to GLAST was observed across all the tissues tested except Mouse Lung, Mouse Liver and Mouse Kidney. In addition to this, a band at ~130 kDa was also observed which could be the glycosylated form of GLAST. Tissue extracts (30 µg lysate) of Mouse Brain (Lane 1), Rat Brain (Lane 2), Mouse Lung (Lane 3) Mouse Liver (Lane 4) and Mouse Kidney (Lane 5) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX)... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-80012
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human EAAT1 (14-42aa RMERFQQGVRKRTLLAKKKVQNITKEDVK).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat brain tissue, mouse brain tissue.
靶标信息
This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: EAAT-1; Excitatory amino acid transporter 1; FLJ25094; GLAST; GLAST-1; Glial glutamate transporter; Glial high affinity glutamate transporter; GluT-1; glutamate transporter; glutamate/aspartate transporter; High-affinity neuronal glutamate transporter; Sodium-dependent glutamate/aspartate transporter 1; Solute carrier family 1 member 3; solute carrier family 1, member 3
基因别名: AI504299; B430115D02Rik; EAAT1; GLAST; GLAST-1; GLAST1; GLU-T; GluT-1; Gmt1; MGluT1; SLC1A3
UniProt ID: (Rat) P24942, (Mouse) P56564
Entrez Gene ID: (Rat) 29483, (Mouse) 20512
glutamate metabolic process
glutamate biosynthetic process
neurotransmitter transport
sensory perception of sound
response to light stimulus
gamma-aminobutyric acid biosynthetic process
response to wounding
response to inorganic substance
L-glutamate transport
cranial nerve development
auditory behavior
sodium ion transmembrane transport
response to drug
malate-aspartate shuttle
response to antibiotic
cell morphogenesis involved in neuron differentiation
positive regulation of synaptic transmission
neuromuscular process controlling balance
L-glutamate import
D-aspartate import
L-glutamate transmembrane transport
positive regulation of defense response to virus by host
transport
dicarboxylic acid transport
response to amino acid
mitophagy in response to mitochondrial depolarization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
