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Invitrogen
GLRX Polyclonal Antibody
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产品信息
PA1-46470
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues 40-100 of an internal portion of human GLRX. [Swiss-Prot# P35754]
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with mouse, rat, rabbit, porcine, bovine based on 100% sequence homology.
This antibody has 91% sequence homology with zebrafish. It is not recommended for ICC/IF applications.
靶标信息
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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