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Invitrogen
GNAI2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-110736
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EEECRQYRAV VYSNTIQSIM AIVKAMGNLQ IDFADPSRAD DARQLFALSC TAEEQGVLPD DLSGVIRRLW ADHGVQACFG RSREYQLNDS AAYYLNDLER
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 96%.
靶标信息
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only two are known so far.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adenylate cyclase-inhibiting G alpha protein; BR; CD49B; G protein; GNAI2; GPIa; GTP-binding regulatory protein Gi alpha-2 chain; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; guanine nucleotide-binding protein G(i), alpha-2 subunit; guanine nucleotide-binding regulatory protein alpha-inhibitory subunit; heterotrimeric guanine nucleotide-binding protein 1C; sGi2; unnamed protein product; VLA-2; VLAA2
基因别名: GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1; HG1C
UniProt ID: (Human) P04899
Entrez Gene ID: (Human) 2771
angiogenesis
adenosine receptor signaling pathway
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
gamma-aminobutyric acid signaling pathway
response to nutrient
positive regulation of cell proliferation
positive regulation of cell migration
positive regulation of superoxide anion generation
positive regulation of urine volume
negative regulation of calcium ion-dependent exocytosis
modulation of synaptic transmission
negative regulation of synaptic transmission
cell division
regulation of calcium ion transport
positive regulation of ERK1 and ERK2 cascade
negative regulation of adrenergic receptor signaling pathway
positive regulation of vascular smooth muscle cell proliferation
positive regulation of neural precursor cell proliferation
negative regulation of apoptotic signaling pathway
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