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Invitrogen
GP130 (extracellular) Polyclonal Antibody
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GP130 (extracellular) Antibody (PA5-77476) in WB
Western blot analysis of mouse brain membrane (lanes 1 and 5), rat brain lysate (lanes 2 and 6), rat brain membrane (lanes 3 and 7) and rat uterus lysate (lanes 4 and 8) with GP130 (extracellular) polyclonal antibody (Product # PA5-77476) using a dilution of 1:400.
产品信息
PA5-77476
产品规格
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)DTLYMVHMAAYTEEG, corresponding to amino acid residues 584-598 of rat GP130
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
靶标信息
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
